Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT9 gene .[ 5] [ 6] [ 7]
FUT9 is one of several alpha-3-fucosyltransferases that can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. FUT9 synthesizes the LeX oligosaccharide (CD15), which is expressed in organ buds progressing in mesenchyma during human embryogenesis.[supplied by OMIM][ 7]
^ a b c GRCh38: Ensembl release 89: ENSG00000172461 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055373 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Kaneko M, Kudo T, Iwasaki H, Ikehara Y, Nishihara S, Nakagawa S, Sasaki K, Shiina T, Inoko H, Saitou N, Narimatsu H (Jul 1999). "Alpha1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX" . FEBS Lett . 452 (3): 237– 42. doi :10.1016/S0014-5793(99)00640-7 PMID 10386598 . S2CID 21861521 . ^ Kaneko M, Kudo T, Iwasaki H, Shiina T, Inoko H, Kozaki T, Saitou N, Narimatsu H (Jan 2000). "Assignment of the human alpha 1,3-fucosyltransferase IX gene (FUT9) to chromosome band 6q16 by in situ hybridization". Cytogenet Cell Genet . 86 (3– 4): 329– 30. doi :10.1159/000015329 . PMID 10575236 . S2CID 85080516 . ^ a b "Entrez Gene: FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)" .
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